Dermal Prints Pathology in down Syndrome

A study of the palmar dermatoglyphics pathology, on a group of 54 mongoloid children (33 boys and 21 girls) in order to know the main malformative stigmata specific to Down syndrome have been set up. A large scale of palmar dermatoglyphic anomalies have been found, most of which were on both hands of patients; they were correlated with a high degree of their somatic, physiological, neuropsychical handicap. The new elements of dermatoglyphic pathology which are added to the other four used so far in the dermatoglyphic diagnosis of Trisomy 21: (L in Hp; the distal displacement of the triradius t’’, the increase of the adt angle and the transverse palmar sulcus), are able to ensure a greater diagnosis accuracy. The identification of the persons with forms of partial Trisomy 21, in mosaic or through balanced translocation, apparently in good health, but having the risk of transmission of the disease to their offsprings in its full or complete form (accompanied by malformations) could prevent this serious disease.